Metabolic Diseases and Cell Signaling Group

(MEDICS)

Group members

Staff scientists

Tamás Csont MD PhD, associate professor, institutional “TDK” coordinator

· Curriculum Vitae

· Publication list (Google Scholar)

· Hungarian Doctoral Council

Csaba Csonka MD PhD, associate professor, educational advisor

· Curriculum Vitae

· Publication list (Google Scholar)

· Hungarian Doctoral Council

Gergő Szűcs MD PhD, research fellow

Renáta Gáspár MSc, PhD, assistant professor

PhD students

Márton Pipicz MD, predoctor

Andrea Sója MSc, 3^rd year

Virág Demján PharmD, 2^nd year

Petra Diószegi MSc, 2^nd year

Márton Szabó MSc, 2^nd year

Technicians

Ilona Ungi

Undergraduate researchers

Mónika Kovács

Zsuzsanna Kovács

Anna Vincze

Róbert Kovács

Nóra Kiss

Dalma Dajka

Vivien Csitkovics

Fanni Márványkövi

Dóra Halmi

Ágnes Jánosi

Katalin Boross

Research interest

In the last few decades, there was an explosive increase in the number of people diagnosed with metabolic diseases including obesity, hyperlipidemia, diabetes mellitus, metabolic syndrome and chronic renal failure, worldwide. It is well known that metabolic diseases have adverse effects on the metabolism. Metabolic diseases significantly increase the incidence and prevalence of cardiovascular diseases which are the leading cause of death amongst adults in the Western world. Thus, our research group is interested in the pathomechanisms of metabolic diseases at a molecular level in different organs. Our main focus is on the myocardium and its adaptive mechanisms. Additionally, we are interested in the development of cytoprotective and cardioprotective diagnostic and therapeutic strategies as well.

Techniques available in the lab

Induction and treatment of metabolic disease models (hyperlipidemia, diabetes mellitus, chronic renal failure etc.) in experimental animals, assessment of cardiac morphology and function (echocardiography, PV catheter), isolated heart perfusion according to Langendorff and working heart perfusion according to Neely, determination of infarct size, induction and maintenance of cell cultures, viability assays, transfection, general biochemical methods to determinate metabolites, proteins and nucleic acids (Western blot, ELISA, PCR, histochemistry, flow cytometry, spectroscopy etc.).

Research field and PhD thesis proposals

Topics for Student's Research Association (TDK) and MA thesis proposals

Best TDK awards of our students in the last decade

Pro Scientia Gold Medal

Márton Pipicz – 2011

Tímea Szegi – 2011

Tamás Baranyai – 2013

OTDT Presentation Award

Tamás Baranyai – 2013

OTDK Awards:

Zoltán Varga, Csaba Tölgyesi – 2007: Special Award, 2009: 3^rd Award

Márta Sárközy – 2009: Special Award, Márta Sárközy, Domitilla Kovács – 2011: Special Award

Márton Pipicz, András Boros, Miklós Nógrády – 2011: 1^st Award

Tímea Szegi, Domitilla Kovács – 2011: 1^st Award

Tamás Baranyai – 2013: 1^st Award

László Kis, Márton Pipicz – 2013: Special Award

Master Teacher Gold Medal of the National Scientific Students' Association

Tamás Csont MD PhD – 2011